Project
Effects of Prenatal Alcohol Exposure on T Cell Function
Principal Investigator(s): Dr. Joanne Weinberg, phone: 604-822-6214; email: joannew@interchange.ubc.ca
Start/End Date: July 2004 – June 2006
Location: UBC, Vancouver, BC
Brief Description: This research investigates the effects of prenatal alcohol exposure on the offspring immune system, with a focus on T cell function
Time Frame: completed
Type of Project: research
Population Served: N/A
Publications: Barr, A.M., Hofmann, C.E., Phillips, A.G., Weinberg, J. & Honer, W.G. (2005) Prenatal ethanol exposure in rats decreases levels of complexin proteins in the frontal cortex. Alcohol. Clin. Exp. Res 29:1915-1920.
Hofmann, C.E., Patyk, I.A. & Weinberg, J. (2005). Prenatal ethanol exposure: Sex difference in anxiety and anxiolytic response to a 5-HT1A agonist. Pharmacol Biochem Behav 82:549-558.
Redila VA, Olson AK, Swann SE. Mohades G, Webber AJ & Weinberg, J. & Christie, B. (2006). Hippocampal cell proliferation is reduced following prenatal ethanol exposure but can be rescued with voluntary exercise. Hippocampus 16:305-311.
Lan, N., Yamashita, F., Halpert, A., Ellis, L., Yu, W., Viau, V. & Weinberg, J. (2006). Prenatal ethanol exposure alters the effects of gonadectomy on hypothalamic-pituitary-adrenal activity in male rats. J. Neuroendo. 18:1-13.
Gabriel, K.G., Yu, C.L., Osborn, J.A. & Weinberg, J. (2006). Prenatal ethanol exposure alters sensitivity to the effects of corticotrophin-releasing factor (CRF) on behavior in the elevated plus maze. Psychoneuroendocrinology 31:1046-1056.
Glavas, M.M., Yu, W.K. & Weinberg, J. (2006). Effects of mineralocorticoid and glucocorticoid receptor blockade on hypothalamic-pituitary-adrenal function in rats prenatally exposed to ethanol. Alcohol Clin Exp Res 30:1916-1924.
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