Project
How Early Life Experiences Alter Immune Function: Effects of Prenatal Ethanol Exposure How Early Life Insults Alter Immune Function: Effects of Prenatal Ethanol Exposure
Principal Investigator(s)/Contact: Dr. Joanne Weinberg, phone: 604-822-6214; email: joannew@interchange.ubc.ca
Location: UBC, Vancouver, BC
Brief Description: This project investigates the effects of prenatal ethanol exposure on T cell responses and cytokine production following challenges to the organism, including immune challenges and stressors.
Time Frame: completed
Type of Project: research
Population Served: N/A
Publications:
Barr AM, Hofmann CE, Phillips AG, Weinberg J & Honer WG, (2005). Prenatal ethanol exposure in rats decreases levels of complexin proteins in the frontal cortes. Alcohol. Clin. Exp. Res 29:1915-1920.
Hofmann CE, Patyk IA & Weinberg J, (2005). Prenatal ethanol exposure: Sex difference in anxiety and anxiolytic response to a 5-HT1A agonist. Pharmacology, Biochemistry & Behavior, 82: 549-558.
Hofmann CE, Ellis L, Yu WK, Weinberg J. Neuroendocrine responses to 5-HT1a and 5-HT2A/C agonists are differentially altered in female and male rodents parentally exposed to ethanal. Alcohol Clin Exp Res, submitted
Gabriel KI, Glavas MM, Ellis LI, Weinberg J (2005). Postnatal handling does not normalize corticotrophin releasing factor mRNA levels in animals prenatally exposed to ethanol. Devel. Brain Res. 157: 74-82
Sliwowska JH, Zhang X, Weinberg J (2005). Prenatal ethanol exposure and fetal programming: Implications for endocrine and immune development and long-term health. In: Miller MW (ed). The Developing Brain: Lessons Learned from Alcohol and Nicotine Exposure. Oxford University Press, in press
Sliwowska JH, Zhang X, Weinberg J (2005). Prenatal ethanol exposure and fetal programming: Implications for endocrine and immune development and long-term health. In: Miller MW (ed). The Developing Brain: Lessons Learned from Alcohol and Nicotine Exposure. Oxford University Press, in press
|
