Project
Magnetoencephalography (MEG) neuroimaging of cognitive processing in children with Fetal Alcohol Spectrum Disorder (FASD)
Principal Investigator(s): Dr. Kim Kerns, Department of Psychology, University of Victoria, phone: 250-721-7553, email: kkerns@uvic.ca; Dr. Jonathon Down, Clay Holyrod, and Jennifer Hill-Karrer
Location: Burnaby, BC and University of Victoria
Description: Purpose of this study is to use MEG to study aspects of inhibition, attention and working memory-using paradigms that have been well established in neuroimaging and electrophysiology studies. While these tasks have been used in the study of the development of executive function across childhood, and are known for sensitivity to behavioural impairment, in a number of neurologic conditions, they haven’t been examined in this population. Three tasks requiring inhibition and working memory will be utilized in the study, a ‘visual flanker’ task, and two specifically designed ‘Go-NoGo’ tasks. These tasks will allow for analyses of key components associated with cognitive processing (P300 wave with attention, contingent negative variation (CNV) with preparatory response set and error-related negativity (ERN) with self monitoring). The MEG at the Down Syndrome Research Foundation in Vancouver is a CTF MEG system. The system has 151 MEG sensors, 32 EEG sensors and 16 trigger channels. The machine’s maximum sample rate is approximately 600 samples per second with a bandwidth of 0 to 1500 Hz.
Kind of Project: research
Time Frame: summer 2006 -
Populations Served: urban young adolescents for the current project
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